Pathology

Division of Clinical Immunology & Immunogenetics

Clinical Immunology

The Division of Clinical Immunology & Immunogenetics is an integration of the former Division of Clinical Immunology and Division of Transplantation & Immunogenetics. The unified Division serves as a central hub that provides comprehensive diagnostic, research and educational services in advanced immunology and transplantation support.

Our Vision

To be a leading immunology and transplantation laboratory that enhances patient safety, success in transplantation, and advances medical care through comprehensive diagnostics, innovative research, and education.

Our Mission

Transplantation and Immunogenetics
  1. Provide comprehensive immunological and transplantation services of international standards.
  2. Support solid organ and stem cell transplantation programs with high-quality compatibility testing and coordination.
  3. Deliver specialist immunological evaluations for immunodeficiency, autoimmunity, allergy, and monoclonal gammopathy.
  4. Act as a quaternary referral center for complex immunological diagnostics not available elsewhere in Hong Kong.
  5. Advance knowledge through clinical research and training of healthcare professionals, scientists, technologists, and students.

Our Service

  1. Immunochemistry: immunoglobulin profiling, tumor markers, cryoglobulin, and monoclonal gammopathy assessment.
  2. Serology: detection and quantitation of autoantibodies, anti-HLA antibodies and anti-HNA antibodies
  3. Cell function laboratory: lymphocyte subset quantitation, immunophenotyping and immune cell function assays.
  4. Molecular diagnostics: Pharmacogenetics, genetic testing for Inborn Error of Immunity, HLA typing, Killer cell Immunoglobulin-like Receptor (KIR) genotyping, Human Neutrophil Antigen (HNA) genotyping and engraftment analysis.
  5. Allergy diagnostics: serological/cell function allergy tests and broader allergy assessments including skin tests and drug allergy testing.
  6. Collaboration with the Department of Medicine in establishing Hong Kong’s first drug allergy clinic under the Hospital Authority.
  7. Transplantation Immunology: Histocompatibility studies and post-transplantation monitoring tests for Solid Organ (SOT) and Haematopoietic Stem Cell Transplantation (HSCT), emergency laboratory support for deceased donor kidney allocation and Paired Kidney Donation Program (PKD)
  8. HLA typing services for the Hong Kong Bone Marrow Donor Registry (HKBMDR) and Hong Kong Red Cross Catherine Chow Cord Blood Bank.
  9. Transplant Laboratory Coordination Centre (TLCC): provides coordination between laboratory and transplant centers in Hong Kong.

Accreditation

  1. College of American Pathologists (CAP, #7175525).
  2. American Society for Histocompatibility and Immunogenetics (ASHI, #06-9-CH-02-1).
  3. National Marrow Donor Program (NMDP) service provider for confirmatory HLA typing.
  4. Accredited by the Hong Kong College of Pathologists and The Royal College of Pathologists Australasia for training in immunopathology.

Research & Education

  1. Active research programs in allergy, neuroimmunology, autoimmunity, transplantation immunology, and immunogenetics.
  2. Educational and training programs for healthcare professionals, scientists, technologists, and students.
  3. Continuous Quality Improvement (CQI) initiatives to monitor performance and enhance patient care.